The Gateway to Missouri River Valley Wine Country
Welcome To Defiance, Missouri
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Historic Defiance, MO  is on Highway 94, 9 miles South of I-64/40. It is only 15 to 20 minutes from West St. Louis County and even closer to the major cities in St. Charles County. Located on the KATY Trail State Park , it attracts bikers and hikers, as well as visitors to the Wineries, Restaurants, Nurseries, B & Bs, Shops and many near by St. Charles County Parks.  

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